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Beilstein J. Org. Chem. 2017, 13, 2922–2927, doi:10.3762/bjoc.13.285
Graphical Abstract
Figure 1: Representative examples of recent 5-HT1AR agonists [3-9].
Scheme 1: Synthesis of FEMPT (7).
Scheme 2: Radiosynthetic scheme for the microfluidic flow synthesis of [18F]fluoroethyltosylate (10) and [18F...
Figure 2: (A) Incorporation yield of [18F]fluoride versus flow rate, red line 180 °C, blue line 150 °C, moder...
Figure 3: Analysis of the final formulated product by LC–MS, using the trapping system to improve the sensiti...